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Enrollment in TOPAZ is now closed.
If you are enrolled and have any questions, please contact us via the
TOPAZ Study Helpdesk: 1-877-37-TOPAZ
[1-877-378-6729]
Thank you to all of our TOPAZ participants
for enrolling and continuing in the study!
What is TOPAZ
Learn more about TOPAZ
Did you know?
People with
Parkinson's Disease and parkinsonism have a higher risk of fracture, especially hip fractures
What is TOPAZ?
The goal of the TOPAZ study is to help PD patients avoid fractures that can lead to loss of quality of life and physical function.
The TOPAZ study will test if an
FDA-approved medicine called zoledronate can prevent fractures and decrease the risk of death in those:
​
-
aged 60 and over
-
with Parkinson's Disease or parkinsonism
-
who have not had a hip fracture
Steps to Join
Online
​
Create a
login to register
As of March 1, 2025,
Enrollment in TOPAZ is now closed.
Thank you for your interest.
Online
Complete the
consent and
health survey
You also might
have an online
video checkup
with a study
doctor
By Mail
​
Receive free vitamin D & take it for a few weeks
Nurse Visit
to your Home
​
Receive a
one-time
45 minute treatment
& receive $100 at enrollment
Every 4 months
​
Check in &
receive $50 per year during the study
Brought to you by...
a nationwide team of doctors
who are experts in bone health and Parkinson’s Disease
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